Annual Report 2024

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Dedicated R&D Centers

Strategic alliances advancing future healthcare

Driven by a shared vision of improving patient health, our dedicated research centers consistently earn recognition from clients for their role in advancing innovation.

In 2007, we established the first dedicated research center, marking the beginning of a unique, long-term partnership model with BMS. Currently, we serve three clients: Amgen, Baxter, and Bristol Myers Squibb. Each strategic alliance has its own trajectory: some have broadened in scope and scale over time; others have also ventured into new scientific domains. Our deep commitment to the success of the alliance ensures flexibility and focus as required. Today, each center boasts ring-fenced infrastructure and is staffed by an exclusive team of multidisciplinary scientists and support personnel, functioning seamlessly as an extension of the client’s internal R&D division. These facilities not only meet regulatory standards but also align with our clients’ internal norms and reflect their practices and culture.

The success of the dedicated centers is underpinned by our commitment to trust and transparency, reinforced by a robust governance model and operational excellence. Our ability to scale scientific talent and enhance our capabilities – both in infrastructure and technology – has been central to meeting our clients’ evolving needs, thereby sustaining these multi-year collaborations.

Syngene Amgen Research & Development Center (SARC)

SARC, a multidisciplinary drug discovery and development center dedicated to Amgen, was established in Bangalore in 2016, building on a relationship that started in 2012. This facility delivers integrated solutions in discovery chemistry and biology, peptide chemistry, antibody and protein reagents, pharmacokinetics and drug metabolism, and pharmaceutical development.

During the year, we strengthened our collaboration by inaugurating a dedicated kilo lab as an extension of the existing center. This addition helps accelerate early development projects which ultimately results in products reaching patients faster.

Baxter Global Research Center (BGRC)

Established in 2013, BGRC marked a decade of innovation and excellence in FY24, celebrating its contributions to Baxter’s mission of saving and sustaining lives. Starting with a team of 70, BGRC now has over 200 dedicated professionals. Our scientists work closely with Baxter on diverse R&D activities, focusing on product and analytical development, as well as pre-clinical evaluations in parenteral nutrition and renal therapy. The expansion in team size and project scope over the years underscores the strategic depth of this collaboration and our ability to provide broad-based, integrated development services.

During the year, BGRC successfully completed several complex projects, ensuring timely global regulatory registrations. The center also demonstrated its expertise in development, validation, and routine testing, particularly in nitrosamine testing, which led to additional investments to further expand these capabilities. Innovation remains a cornerstone of our operations at BGRC, with new projects initiated in oncology.

Biocon Bristol Myers Squibb Research & Development Center (BBRC)

The BBRC collaboration, having celebrated its 25th anniversary, continued to deliver against research and development targets for BMS. During the year, there was further growth in the number of scientific FTEs supporting research and early development projects, and added laboratory infrastructure. The team also consolidated its capabilities in translational medicine by incorporating good clinical practices in their laboratories.

In fiscal year 2024, it gave us great pleasure to receive BMS leaders, Dr Robert Plenge, Executive Vice President, Chief Research Officer and Head of Research and Karin Shanahan, Executive Vice President of Global Product Development and Supply as visitors on our Bangalore and Mangalore campuses.

“For nearly three decades, our partnership with Syngene has provided key support to our R&D pipeline and has laid the groundwork for Bristol Myers Squibb to expand our global R&D efforts in India, a country with a rich talent pool aligned with our areas of focus. We look forward to our continued successful collaboration, as we grow our local R&D engine and accelerate our pipeline.”

Michael Ellis Senior Vice President, Head, Small Molecule Drug Discovery, Bristol Myers Squibb

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